Hepatic hydrothorax as a rare complication of cirrhosis. A therapeutic challenge in advanced cirrhosis

Authors

DOI:

https://doi.org/10.52784/27112330.160

Keywords:

hepatic, hydrothorax, pleural effusion, cirrhosis, hepatitis C virus.

Abstract

Hepatic hydrothorax is a rare entity in patients with cirrhosis. To date, several therapeutic alternatives have been proposed, both medical and surgical, prior to liver transplantation as the definitive management. Here we present the case of a 78-year-old patient with cirrhosis secondary to hepatitis C virus infection, who consulted the emergency department for respiratory distress, documenting a massive right pleural effusion of transudate type, which responded partially to diuretic therapy and drainage with pigtail, and later died due to hemorrhagic complications associated with cirrhosis. It is important to describe this pathology given its low frequency in patients with cirrhosis and the therapeutic challenges we face with the limited currently available evidence.

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Author Biographies

Melissa Lara-Viáfara, Universidad Libre de Colombia

Médica, Residente de Medicina Interna, Universidad Libre de Colombia, Sede Cali. Grupo Interinstitucional de Medicina Interna (GIMI 1). Cali, Colombia.

Mauricio Salazar-Moreno, Universidad Libre de Colombia

Médico, Especialista en Geriatría Clínica, Especialista en Gerencia de Servicios de Salud. Residente Medicina Interna, Universidad Libre de Colombia, Sede Cali. Grupo Interinstitucional de Medicina Interna (GIMI 1). Cali, Colombia.

Juliana Suárez-Correa, Clínica Farallones

Médica, Especialista en Cirugía General, Especialista en Gastroenterología y Endoscopia Digestiva, Departamento de Gastroenterología y Endoscopia, Clínica Farallones. Cali, Colombia.

Oscar Reyna-Carrasco, Clínica Rafael Uribe Uribe, Universidad Libre

Médico, Especialista en Medicina Interna, Clínica Rafael Uribe Uribe. Docente, Universidad Libre. Cali, Colombia.

References

Banini BA, Alwatari Y, Stovall M, Ogden N, Gershman E, Shah RD, et al. Multidisciplinary management of hepatic hydrothorax in 2020: An evidence-based review and guidance. Hepatology 2020;72:1851-1863. https://doi.org/10.1002/hep.31434.

Badillo R, Rockey DC. Hepatic hydrothorax: clinical features, management, and outcomes in 77 patients and review of the literature. Medicine (Baltimore) 2014;93:135-142. https://doi.org/10.1097/md.0000000000000025.

Morrow CS, Kantor M, Armen RN. Hepatic hydrothorax. Ann Intern Med 1958;49:193-203. https://doi.org/10.7326/0003-4819-49-1-193.

Lv Y, Han G, Fan D. Hepatic hydrothorax. Ann Hepatol 2018;17:33-46. https://doi.org/10.5604/01.3001.0010.7533.

Huang PM, Chang YL, Yang CY, Lee YC. The morphology of diaphragmatic defects in hepatic hydrothorax: thoracoscopic finding. J Thorac Cardiovasc Surg 2005;130:141-145. https://doi.org/10.1016/j.jtcvs.2004.08.051.

Xiol X, Tremosa G, Castellote J, Gornals J, Lama C, Lopez C, et al. Liver transplantation in patients with hepatic hydrothorax. Transpl Int 2005;18:672-675. https://doi.org/10.1111/j.1432-2277.2005.00116.x.

Siegerstetter V, Deibert P, Ochs A, Olschewski M, Blum HE, Rössle M. Treatment of refractory hepatic hydrothorax with transjugular intrahepatic portosystemic shunt: long-term results in 40 patients. Eur J Gastroenterol Hepatol 2001;13:529-534. https://doi.org/10.1097/00042737-200105000-00011.

Ditah IC, Al Bawardy BF, Saberi B, Ditah C, Kamath PS. Transjugular intrahepatic portosystemic stent shunt for medically refractory hepatic hydrothorax: A systematic review and cumulative meta-analysis. World J Hepatol 2015;7:1797-1806. https://doi.org/10.4254/wjh.v7.i13.1797.

Cardenas A, Kelleher T, Chopra S. Review article: hepatic hydrothorax. Aliment Pharmacol Ther 2004;20:271-279. https://doi.org/10.1111/j.1365-2036.2004.02081.x.

Kaplan LM, Epstein SK, Schwartz SL, Cao QL, Pandian NG. Clinical, echocardiographic, and hemodynamic evidence of cardiac tamponade caused by large pleural effusions. Am J Respir Crit Care Med 1995;151:904-908. https://doi.org/10.1164/ajrccm/151.3_Pt_1.904.

Garbuzenko DV, Arefyev NO. Hepatic hydrothorax: An update and review of the literature. World J Hepatol 2017;9:1197-1204. https://doi.org/10.4254/wjh.v9.i31.1197.

Runyon BA. Introduction to the revised American Association for the Study of Liver Diseases Practice Guideline management of adult patients with ascites due to cirrhosis 2012. Hepatology 2013;57:1651-1653. https://doi.org/10.1002/hep.26359.

Morando F, Rosi S, Gola E, Nardi M, Piano S, Fasolato S, et al. Adherence to a moderate sodium restriction diet in outpatients with cirrhosis and ascites: a real-life cross-sectional study. Liver Int 2015;35:1508-1515. https://doi.org/10.1111/liv.12583.

Dumortier J, Leprêtre J, Scalone O, Boillot O, Scoazec JY, Delafosse B, et al. Successful treatment of hepatic hydrothorax with octreotide. Eur J Gastroenterol Hepatol 2000;12:817-820. https://doi.org/10.1097/00042737-200012070-00018.

Liu LU, Haddadin HA, Bodian CA, Sigal SH, Korman JD, Bodenheimer HC, Jr., et al. Outcome analysis of cirrhotic patients undergoing chest tube placement. Chest 2004;126:142-148. https://doi.org/10.1378/chest.126.1.142.

Liu WL, Kuo PH, Ku SC, Huang PM, Yang PC. Impact of therapeutic interventions on survival of patients with hepatic hydrothorax. J Formos Med Assoc 2010;109:582-588. https://doi.org/10.1016/s0929-6646(10)60095-2.

Dhanasekaran R, West JK, Gonzales PC, Subramanian R, Parekh S, Spivey JR, et al. Transjugular intrahepatic portosystemic shunt for symptomatic refractory hepatic hydrothorax in patients with cirrhosis. Am J Gastroenterol 2010;105:635-641. https://doi.org/10.1038/ajg.2009.634.

Spencer EB, Cohen DT, Darcy MD. Safety and efficacy of transjugular intrahepatic portosystemic shunt creation for the treatment of hepatic hydrothorax. J Vasc Interv Radiol 2002;13:385-390. https://doi.org/10.1016/s1051-0443(07)61741-2.

Campos S, Gomes D, Sofia C. Transjugular intrahepatic portosystemic shunt in refractory hydrothorax - a contribution to an unexplored indication. Eur J Gastroenterol Hepatol 2016;28:661-666. https://doi.org/10.1097/meg.0000000000000623.

Published

2022-07-05

How to Cite

Lara-Viáfara, M., Salazar-Moreno, M., Suárez-Correa, J., & Reyna-Carrasco, O. (2022). Hepatic hydrothorax as a rare complication of cirrhosis. A therapeutic challenge in advanced cirrhosis. Hepatología, 3(2), 218–224. https://doi.org/10.52784/27112330.160

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Case reports
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