Antivirales de acción directa contra la hepatitis C: revisión narrativa

Autores/as

DOI:

https://doi.org/10.59093/27112330.109

Palabras clave:

hepatitis c, antivirales, respuesta viral sostenida, genotipo, reacciones adversas, resistencia medicamentosa.

Resumen

Desde los años ochenta se ha explorado el tratamiento para el virus de la hepatitis C, aunque en ese entonces los medicamentos disponibles eran poco toleradas y poco eficaces. En el 2011, la introducción de antivirales de acción directa transformó significativamente el curso de la enfermedad, logrando tasas de curación superiores al 90 % en los pacientes. Este avance ha permitido prevenir complicaciones futuras con efectos adversos mínimos. La presente revisión aborda la línea de tiempo del descubrimiento de los antivirales, su mecanismo de acción, sus indicaciones y potencial impacto en la salud pública.

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Biografía del autor/a

Laura Cristina Gómez-Moreno, Universidad de Antioquia

Estudiante de Medicina, Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia.

Samuel David García-Vega, Universidad de Antioquia

Estudiante de Medicina, Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia.

Anlly Paola Pineda-García, Universidad de Antioquia

Estudiante de Medicina, Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia.

María Adelaida Lopera-Baena, Universidad de Antioquia

Estudiante de Medicina, Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia.

Andrés Fernando Rodríguez-Gutiérrez, Universidad de Antioquia

Médico, Especialista en Medicina Interna, MSc en Epidemiología, Fellow de Hepatología, Universidad de Antioquia. Medellín, Colombia.

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Publicado

2024-05-02

Cómo citar

Gómez-Moreno, L. C., García-Vega, S. D., Pineda-García, A. P., Lopera-Baena, M. A., & Rodríguez-Gutiérrez, A. F. (2024). Antivirales de acción directa contra la hepatitis C: revisión narrativa. Hepatología, 5(2), 123–136. https://doi.org/10.59093/27112330.109

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